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NAMPT inhibitor-linker 1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112615
    NAMPT inhibitor-linker 1

    		Drug-Linker Conjugates for ADC Cancer
    NAMPT inhibitor-linker 1 is a agent-linker conjugates for ADC, composed of an NAMPT inhibitor as a payload, and a linker. ADC-3 consists of an NAMPT inhibitor-linker 1 and an anti-c-Kit monoclonal antibody, exihibits potent activity against c-Kit expressing cell lines such as GIST-T1 and NCI-H526 cells, with IC50s of <3 pM and 9 pM, respectively.
    <em>NAMPT</em> <em>inhibitor-linker</em> 1

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